Abstract:   NMEA0183 protocol parsing module is crucial in a navigation system software module, the module of the robustness and efficiency is directly related to the performance of the whole navigation system. In order to timely and effective resolution NMEA data flow, separate processing NMEA data flow analysis and data display, reduce the coupling of parsing module and display module, put forward a kind of based on regular expressions, and based on the MVC architecture of NMEA0183 protocol parsing methods.The whole parsing module can be divided into four stages, the original NMEA data stream storage, NMEA data flow efficient parsing, NMEA data validation, NMEA data show.At present the method has been applied to the GPS navigation products, the measured show that the analytical module, high efficiency and reliable data flow analysis showed good realtime.